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KMID : 0363619970180010344
Journal of Korean Oriental Medicine
1997 Volume.18 No. 1 p.344 ~ p.356
The effect of Sojadodamgangkitang on the pulmonary injury caused by SO_2 in rats
Park Dong-Il

Kim Bong-Jae
Abstract
This experiment was performed in order to study the clinical effect of Sojadodamgangkitang on the pulmonary injury caused by SO_2. Healthy adult male rats weighing about 250g were divided into 4 groups-the Normal group, the Control group, the group of Sojadodamgangkitang administration for 5 days after SO_2 gas exposure(Sample I), and the group of Sojadodamgangkitang administration for 10 days before and for 5days after SO_2 gas exposure(Sample II). The results were obtained as. follows; 1. In comparison with Control group, Sample I and Sample II were revealed significant effect on the total number of leucocyte. 2. In comparison with Control group, Sample I and Sample II were revealed significant effect on. the erythrocyte sedimentation rate. 3. In the effect on the lung weight, Sample I and Sample II were revealed significantly. 4. In the effect on the lung TBA level, only Sample II was revealed significantly. 5. In the effect on the tracheal glycoprotein level, Sample I and Sample II were revealed significantly. According to above results, Sojadodamgangkitang had significant effect on the pulmonary injury caused by SO_2 in rats.
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